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Cycloheximide (放线菌酮) 上海浩然生物热销中

来宝网 2011/3/10点击3337次

Cycloheximide  放线菌酮

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品 名:放线菌酮, 环已酰亚胺

英文名称：actidione, Cycloheximide, Naramycin A

说明:由产生放线菌酮的放线菌发酵液中提得的一种抗生素。无色晶体。熔点119~121℃。易溶于甲醇、乙醇和丙酮，微溶于水。耐酸、耐热。在碱性情况下易分解。对酵母菌、霉菌、原虫等病原菌等有抑制作用。对细菌无显著抑制作用。农业上，用于防治樱桃叶斑病、樱花穿孔病、桃树菌核病、橡树立枯病、薄荷及松树的疱锈病、甘薯黑疤病、菊花黑星病和玫瑰的霉病等。此外，也是鼠类、兔子、狗熊、野猪等的忌避剂。也可由链霉素、制霉菌素等发酵液中的副产物制得。

性状: 无色片状结晶。2℃时溶解度(g/100ml)：水中2.1，乙酸戊酯7.0。溶于氯仿、乙醇、乙醚、丙酮和甲醇。

熔点:119.5-121℃(115-116℃)，比旋光度[α]D25 +6.8?(c=2，水中)，[α]D29+3.38?(c=9.47，甲醇中)。有毒，半数致死量(小鼠，静脉)150mg/kg。有刺激性.

Sigma相关产品资料：

Sigma  C7698 Cycloheximide from microbial, ≥94% (TLC)

Synonym:

3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide, Actidione, Naramycin A

CAS Number:

66-81-9

Linear Formula:

C15H23NO4

Molecular Weight:

281.35

Beilstein Registry Number:

88868

EC Number:

200-636-0

MDL number:

MFCD00082346

PubChem Substance ID:

24892981

Description

Biochem/physiol Actions

Cycloheximide (CHX) is an antibiotic produced by S. griseus. Its main biological activity is translation inhibition in eukaryotes resulting in cell growth arrest and cell death. CHX is widely used for selection of CHX-resistant strains of yeast and fungi, controlled inhibition of protein synthesis for detection of short-lived proteins and super-induction of protein expression, and apoptosis induction or facilitation of apoptosis induction by death receptors.

性质

biological source

from microbial

assay

≥94% (TLC)

solubility

ethanol: soluble, clear to hazy

Gene Information

human ... FKBP1A(2280), PIN1(5300)

storage temp.

2-8°C

安全性

Personal Protective Equipment

Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

Hazard Codes

T+,N

Risk Statements

61-28-51/53-68

Safety Statements

53-45-61

RIDADR

UN2811 6.1/PG 1

WGK Germany

3

RTECS

MA4375000

品名

产地

货号

规格

单价

备注

Cycloheximide; 放线菌酮 ;环已酰亚胺 ;Actidione ;Naramycin A

Sigma

C7698

1G

询价

现货

Cycloheximide; 放线菌酮 ;环已酰亚胺 ;Actidione ;Naramycin A

Sigma

C7698

5G

询价

现货

 

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