来宝网移动站

Synonym:

1,3,5-Estratriene-3,17β-diol, 17β-Estradiol, 3,17β-Dihydroxy-1,3,5(10)-estratriene, Dihydrofolliculin

CAS Number:

50-28-2

Linear Formula:

C₁₈H₂₄O₂

Molecular Weight:

272.38

Beilstein Registry Number:

1914275

EC Number:

200-023-8

MDL number:

MFCD00003693

PubChem Substance ID:

24278426

Biochem/physiol Actions

The major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female phenotype in embryogenesis and during puberty by regulating gene transcription and, thus, protein synthesis. It also induces the production of gonadotropins which, in turn, induce ovulation. Exposure to estradiol increases breast cancer incidence and proliferation.

assay

≥98%

mp

176-180 °C(lit.)

Gene Information

human ... ESR1(2099), ESR2(2100), ESRRA(2101), ESRRB(2103), GPER(2852), SERPINA6(866)

rat ... Afp(24177), Ar(24208), Esr1(24890), Esr2(25149), Shbg(24775)

mouse ... Esr1(13982), Esr2(13983), Esrra(26379)

Personal Protective Equipment

Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

Hazard Codes

T

Risk Statements

45

Safety Statements

53-45

WGK Germany

3

RTECS

KG2975000