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CA15-3
The MUC-1 cancer antigen is a mucin-type glycoprotein. The Ma552 and Ma695 antibodies to MUC-1 were characterized in the ISOBM TD4-workshop. The Ma552 monoclonal antibody epitope is located in the mucin polypeptide core and recognizes the hexapeptide [TRPAPG].
The Ma695 monoclonal antibody recognizes a sialylated carbohydrate epitope expressed on MUC-1 mucin.
| MAb | Isotype | Form | Prod. no. | Comments |
|---|
| Ma552 | IgG1 | Purified | 209-01 | Specific for the tandem repeat of the MUC-1 core protein (analogue to DF3). Epitope [TRPAPG]. |
| Ma695 | IgG1 | Purified | 204-01 | Carbohydrate on MUC 1 (analogue to 115D8) |
| 115D8 | IgG2b | Purified | 201-480 | Carbohydrate on muc-1 |
| DF3 | IgG1 | Purified | 201-485 | Specific for the tandem repeat of the MUC-1 core protein. Epitope [DTRPAP] |