上海交通大学Bio-X中心 Bio-X Center of Shanghai Jiao Tong University www.bio-x.cn
上海交通大学Bio-X中心(以下简称“中心”)是于2005年由NHGG(Neuropsychiatric and Human Genetics Group, 神经精神与人类遗传学研究室)和2000年成立的Bio-X生命科学研究基地经过重组凝练而成。自从谢绳武校长亲自宣布了“中心”的成立起，标志了我校正式启动了生命学科与其他多学科间进行交叉合作研究基地的建设，开始起到成为从事与生命科学相关的多学科交叉研究科学家的工作平台的作用，并为不同学科和领域的研究人员和学生提供一个学术思想和信息交流的“家”。
中心现届主任为贺林教授(中国科学院院士)，名誉主任为诺贝尔奖获得者朱棣文教授。中心目前由具有不同学术背景的国内外资深研究者和特聘教授领导的“核心”和“卫星”研究室，以及一批优秀、富有创造性的年轻学者、讲究实效的技术支撑人员、认真严格的行政管理人员，一群年轻聪明的研究生和博士后组成。经过多年的摸索和实践，最终中心把自己的研究方向定位在《疾病与健康》、《营养与健康》、《发育与生殖》、《生物安全》、《DNA计算与技术》的范畴，具体可分解为“基因定位与克隆”、“功能基因组学”、“药物基因组学”、“精神疾病代谢组学”、“蛋白质组学”、“动物模型”、“DNA计算与技术”、“生物信息学”、“全国遗传资源保护网”等内容。
目前中心拥有世界一流研究设施，大于2000平方米的研究空间(包括分布于上海交通大学徐汇校区浩然高科技大厦五楼、科技馆、卫生科楼、闵行校区生命楼、Bio-X附属医院以及中科院生科院上海营养科学研究所等多处研究空间)，申请到了几乎所有不同类型的国家和地方的项目基金。经过以往的努力，中心先后荣获上海市科学技术一等奖1项，教育部科学技术(自然科学)一等奖1项，国家自然科学二等奖1项，以及其它各类殊荣多项。此外，在交大史上赢得了至少三个第一：第一个973首席科学家，第一个自然科学系列《自然遗传》杂志论文，第一个国家自然科学二等奖。发表SCI论文200余篇，主编和参编专著10部，申请和获取专利10多项。
中心在新时期的新策略包括：
1、加大时空延伸：Bio-X中心/长宁绿地医院共建“精神神经科学和系统代谢组学研究所”；Bio-X中心/上海精神卫生中心间重建基础研究基地；Bio-X中心/企业间共同发展之路；Bio-X中心/阿斯利康第二期合作；Bio-X中心/罗氏的第二期合作；上海交通大学Bio-X中心/中科院营养所共建基地。
2、增强研究深度：详细研讨与部署了对下一阶段攻克精神疾病、营养相关疾病以及骨骼发育疾病的方案与措施。
3、走新产学研路：疾病基因组学、营养基因组学和药物基因组学等以及DNA技术的研究将与产品的产业化纵横穿插、共同推进，努力缩短科学研究回报社会和民众的时间与距离。
Bio-X中心自成立之日起，始终把如何提高人类生活质量作为研究工作开展的中心，把为“科教兴国”和提高我国科研国际地位出一份力量作为一切工作的基本点。中心的核心思维是不求多，只求精，踏踏实实地做好几件事。目前的中心正紧踏“健康中国人，健康上海人”的节拍，切切实实地为民族振兴、国家富强、人民健康做努力！
In 2005 the Bio-X Center of Shanghai Jiao Tong University was formed by bringing together NHGG (the Neuropsychiatric and Human Genetics Group) founded in March 1996 and the Bio-X Life Science Research Center established in April 2000. The mission of the Center is to provide a working platform for scientists engaged in interdisciplinary research in the field of life sciences and a forum for the exchange of ideas and information among research fellows and students from different disciplines and fields. The current director of the Center is Prof. Lin He, fellow of Chinese Academy of Sciences, and the honorary director is Prof. Steve Zhu, a Nobel Prize Laureate.
The Center, consisting of a number of "core" and project-oriented "satellite" groups made up of high-caliber academics, senior researchers and specially appointed professors from both home and abroad, creative young scholars, technical support and administrative management personnel, as well as a number of postgraduates and post-doctoral fellows from various academic backgrounds, possesses world cutting-edge facilities and more than 2000 M2 of research space. The Center also boasts success in winning many types of project funds at both national and regional levels and has won various honors, including First Prize in the Shanghai Science and Technology Awards, First Prize in the Science and Technology Awards of the Chinese Ministry of Education, and Second Prize in the National Natural Science Awards. Furthermore, the Center enjoys at least three "Firsts" in the history of Shanghai Jiao Tong University: It produced the first leading scientist in the National 973 Program, was first to have a scientific paper published in Nature Genetics, and by obtaining the Second Prize, first to achieve success in the National Natural Science Awards.
The Center, while providing an open intellectual atmosphere and a wide-ranging research environment, aims to maintain an ethical and responsible approach to scientific endeavor, while being oriented to meeting key state requirements and to maintain a pioneering and innovative spirit. The Center is keenly aware that learning has to be based on solid principles of scientific method and a long term approach rather than the pursuit of quick success. As a result of its endeavors over a number of years the Center has created and accumulated an impressive pool of intellectual resources for our country and has built a rigorous and systematic research methodology geared to meeting today's scientific challenges. The current work modules include genetic mapping and cloning, functional genomics, pharmacogenomics, proteomics, DNA computing, bioinformatics, technical support, and national genetic resources protection network, etc.
The Center has an ambitious medium and long term programme of wide ranging and cross-disciplinary projects which include:
(1) EXPANSION PROJECTS:
The establishment of a Institute for Neuropsychiatric Sciences and Metabonomics in co-operation with Changning Greenland Hospital;
The establishment of a Bio-X Center Hospital;
The establishment of a National Sample Bank;
The establishment of a Developmental and Reproductive Research Base;
The establishment of a Nutrition and Health Research Base in conjunction with the Institute for Nutritional Sciences, CAS;
The establishment of a fundamental scientific research unit in co-operation with the Shanghai Mental Health Center;
The establishment of an Academy for Suzhou Yangzi Delta Systematic Bio-X Science in conjunction with the Jiangsu Wuzhong Group;
The launch of Phase 2 of a co-operative venture with AstraZeneca;
The continuation of Phase 2 of a co-operative venture with Roche.
(2) BASIC RESEARCCH:
The center has a fully developed programme of research in nutrition and health related areas, particularly those affecting mental health.
(3) LINKS WITH INDUSTRY: Where appropriate, the Center aims to speed up the application of translational medicine or to give its research an industrial orientation by applying its expertise in the genomics of disease, nutrition and drugs to shorten the time taken for new scientific discoveries to bring real, practical benefits to the population as a whole.