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β-Amyloid (1-42)
品牌:MedChemExpress (MCE)
货号:HY-P1363A
CAS:107761-42-2
Synonyms:Amyloid β-peptide (1-42 (human
生物活性:β-淀粉样蛋白(1-42),人(淀粉样蛋白β-肽(1-42),人)是一种由 42 个氨基酸组成的肽,在阿尔茨海默病的发病机制中起关键作用[1][2][3]。
体内:β-Amyloid (1-42), human TFA 可用于动物建模,构建阿尔兹海默症模型。 MCE尚未独立证实这些方法的准确性。仅供参考。
参考文献:
[1]. Solntseva EI, et al. Impact of amyloid-β peptide (1-42) on voltage-gated ion currents in molluscan neurons. Bull Exp Biol Med. 2011 Oct;151(6):671-4.
[2]. Barucker C, et al. Nuclear translocation uncovers the amyloid peptide Aβ42 as a regulator of gene transcription. J Biol Chem. 2014 Jul 18;289(29):20182-91.
[3]. Stefania Sabella, et al. Capillary electrophoresis studies on the aggregation process of beta-amyloid 1-42 and 1-40 peptides. Electrophoresis. 2004 Oct;25(18-19):3186-94.