yao用级二氧化碳原料药测定专用净化装置HHO-IIIPurification device
yao用级二氧化碳原料药测定专用净化装置HHO-IIIPurification device 详细信息：
二氧化碳（carbon dioxide），一种碳氧化合物，化学式为CO2，化学式量为44.0095，常温常压下是一种无色无味或无色无臭而其水溶液略有酸味的气体，也是一种常见的温室气体，还是空气的组分之一（占大气总体积的0.03%-0.04%）。YAO用级二氧化碳含CO2不得少于99.5%(ml/ml)。
碳氢化合物 取本品作为供试品；取甲烷含量为0.0020%的气体（以氮气为稀释剂）作为对照气体，照气相色谱法（通则0521）试验，用玻璃球为填料的色谱柱（0.8m×4mm，80目）；柱温为110℃；进样口温度为110℃；检测器温度为120℃。量取供试品气体与对照气体，注入气相色谱仪，在净化温度为360℃时测得的峰面积为相应空白值；量取供试品气体与对照气体，注入气相色谱仪，测定峰面积，减去相应空白值后的峰面积为校正峰面积。按外标法以校正峰面积计算，含碳氢化合物（以甲烷计）不得过0.0020%。
浩瀚色谱（山东）应用技术开发有限公司，研制的药典二氧化碳净化装置，净化效果好，采用标气进行空白试验，在安捷伦7820A，7890,8860,8890气相色谱仪上安装简单，用户可以安装，无XU改造仪器，增加了仪器的多层功能，满足YAO典2020年版四部：二氧化碳的指标要求。
yao用级二氧化碳原料药测定专用净化装置HHO-IIIPurification device 测试谱图：
HHO-IIIPurification device for the determination of Yao grade carbon dioxide raw materials
Detailed information on the HHO-IIIPurification device for the determination of Yao grade carbon dioxide raw materials:
Carbon dioxide, a carbon oxide compound with a chemical formula of CO2 and a chemical formula of 44.0095, is a colorless, odorless, or colorless gas with a slightly acidic aqueous solution at room temperature and pressure. It is also a common greenhouse gas and a component of air (accounting for 0.03% -0.04% of the total volume of the atmosphere). The CO2 content of YAO grade carbon dioxide shall not be less than 99.5% (ml/ml).
Take this product as the test sample for hydrocarbons; Take a gas with a methane content of 0.0020% (using nitrogen as the diluent) as the control gas, and perform gas chromatography (General Rule 0521) according to the test. Use a glass ball packed chromatographic column (0.8m x 4mm, 80 mesh); The column temperature is 110 ℃; The inlet temperature is 110 ℃; The detector temperature is 120 ℃. Measure the gas of the test sample and the control gas, inject them into the gas chromatograph, and the peak area measured at a purification temperature of 360 ℃ is the corresponding blank value; Measure the gas of the test sample and the control gas, inject them into the gas chromatograph, measure the peak area, and subtract the corresponding blank value to obtain the corrected peak area. According to the external standard method for correcting peak area, the content of hydrocarbons (calculated as methane) shall not exceed 0.0020%.
Haohan Chromatography (Shandong) Application Technology Development Co., Ltd. has developed a pharmacopoeia carbon dioxide purification device with good purification effect. It uses standard gas for blank testing and is easy to install on the Agilent 7820A, 789088608890 gas chromatographs. Users can install the device without XU modification, which increases the multi-layer function of the instrument and meets the indicator requirements for carbon dioxide in the 2020 edition of the YAO Pharmacopoeia.
The testing spectrum of the HHO-IIIPurification device for the determination of Yao grade carbon dioxide raw materials: