pH荧光探针Protonex红670酸…

pH荧光探针Protonex红670酸货号21181
产品简介
详细介绍
  • 参考报价:电议 产地:陕西 品牌:AAT Bioquest 型号:21181 更新时间:2024/3/28
pH荧光探针Protonex 红 670 酸 货号21181参数
Ex (nm)-Em (nm)-
分子量N/A溶剂DMSO
存储条件在零下15度以下保存, 避免光照

pH荧光探针Protonex 红 670 酸 货号21181概述

pH荧光探针Protonex 红 670 酸 货号21181基本信息

产品名称:Protonex 红 670 酸

储存条件:-15℃避光防潮

保质期:12个月

 

pH荧光探针Protonex 红 670 酸 货号21181物理化学光谱特性

分子量:629.76

外观:固体

溶剂:DMSO

激发波长(nm):N/A

发射波长(nm):N/A

 

pH荧光探针Protonex 红 670 酸 货号21181介绍

Protonex Red 670 的工作原理是根据环境 pH 值改变其荧光强度。 Protonex? Red 670 在碱性 pH 值下荧光zui小,在酸性 pH 下荧光zui大。当 Protonex? Red 670 与细胞表面的受体或抗体结合时,它基本上不发出荧光,因为细胞外 pH 值为中性。然而,当受体或抗体响应刺激而内化到细胞中时,它会进入内体途径,其中 pH 值为酸性。这会导致 Protonex? Red 670 在受到红色激光(例如 632 nm He-Ne 或 647 nm 红色激光)激发时发出强荧光并发出红光。通过测量 Protonex? Red 670 的荧光强度,可以监测活细胞中受体或抗体的激活和运输。 Protonex? Red 670 在研究 G 蛋白偶联受体 (GPCR)(zui流行的治疗药物靶点之一)的激活和运输方面特别有用。 Protonex? Red 670 可用于标记任何受体或表位标签抗体,并监测其在激动剂刺激下从细胞表面进入酸性内体的运动。 Protonex? Red 670 还可用于测量活细胞中不同 GPCR 的gao效激动剂和拮抗剂反应,例如 TRHR-1 和 β-肾上腺素受体的激活,这两种 GPCR 涉及激素调节和心血管功能。百萤生物是AAT Bioquest的zhong国代理商,为您提供优质的Protonex 红 670 酸。 

 

溶解方案(溶剂以说明书为准)


0.1 mg0.5 mg1 mg5 mg10 mg
1 mM158.791 μL793.953 μL1.588 mL7.94 mL15.879 mL
5 mM31.758 μL158.791 μL317.581 μL1.588 mL3.176 mL
10 mM15.879 μL79.395 μL158.791 μL793.953 μL1.588 mL

 

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mOrange2, a Genetically Encoded, pH Sensitive Fluorescent Protein, is an Alternative to BCECF-AM to Measure Intracellular pH to Determine NHE3 and DRA Activity.
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