Increased LCN2 (lipocalin 2) in the RPE decreases autophagy and activates inflammasome-ferroptosis processes in a mouse model of dry AMD.
Authors: Gupta, Urvi and Ghosh, Sayan and Wallace, Callen T and Shang, Peng and Xin, Ying and Nair, Archana Padmanabhan and Yazdankhah, Meysam and Strizhakova, Anastasia and Ross, Mark A and Liu, Haitao and Hose, Stacey and Stepicheva, Nadezda A and Chowdhury, Olivia and Nemani, Mihir and Maddipatla, Vishnu and Grebe, Rhonda and Das, Manjula and Lathrop, Kira L and Sahel, José-Alain and Zigler, J Samuel and Qian, Jiang and Ghosh, Arkasubhra and Sergeev, Yuri and Handa, James T and St Croix, Claudette M and Sinha, Debasish
Journal: Autophagy (2023): 92-111
cGAMP-activated cGAS-STING signaling: its bacterial origins and evolutionary adaptation by metazoans.
Authors: Patel, Dinshaw J and Yu, You and Xie, Wei
Journal: Nature structural & molecular biology (2023): 245-260
cGLRs are a diverse family of pattern recognition receptors in animal innate immunity.
Authors: Li, Yao and Slavik, Kailey M and Morehouse, Benjamin R and de Oliveira Mann, Carina C and Mears, Kepler and Liu, Jingjing and Kashin, Dmitry and Schwede, Frank and Kranzusch, Philip J
Journal: bioRxiv : the preprint server for biology (2023)
Signal strength of STING activation determines cytokine plasticity and cell death in human monocytes.
Authors: Kabelitz, Dieter and Zarobkiewicz, Michal and Heib, Michelle and Serrano, Ruben and Kunz, Monika and Chitadze, Guranda and Adam, Dieter and Peters, Christian
Journal: Scientific reports (2022): 17827
cGAS/cGAMP/STING signal propagation in the tumor microenvironment: Key role for myeloid cells in antitumor immunity.
Authors: Mekers, Vera E and Kho, Vera M and Ansems, Marleen and Adema, Gosse J
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology (2022): 158-167
How autophagy controls the intestinal epithelial barrier.
Authors: Foerster, Elisabeth G and Mukherjee, Tapas and Cabral-Fernandes, Liliane and Rocha, Juliana D B and Girardin, Stephen E and Philpott, Dana J
Journal: Autophagy (2022): 86-103
Structural basis for c-di-AMP-dependent regulation of the bacterial stringent response by receptor protein DarB.
Authors: Heidemann, Jana L and Neumann, Piotr and Krüger, Larissa and Wicke, Dennis and Vinhoven, Liza and Linden, Andreas and Dickmanns, Achim and Stülke, J?rg and Urlaub, Henning and Ficner, Ralf
Journal: The Journal of biological chemistry (2022): 102144
STING agonist diABZI induces PANoptosis and DNA mediated acute respiratory distress syndrome (ARDS).
Authors: Messaoud-Nacer, Yasmine and Culerier, Elodie and Rose, Stéphanie and Maillet, Isabelle and Rouxel, Nathalie and Briault, Sylvain and Ryffel, Bernhard and Quesniaux, Valerie F J and Togbe, Dieudonnée
Journal: Cell death & disease (2022): 269
Sequence Conservation, Domain Architectures, and Phylogenetic Distribution of the HD-GYP Type c-di-GMP Phosphodiesterases.
Authors: Galperin, Michael Y and Chou, Shan-Ho
Journal: Journal of bacteriology (2022): e0056121
T cell-intrinsic STING signaling promotes regulatory T cell induction and immunosuppression by upregulating FOXP3 transcription in cervical cancer.
Authors: Ni, Huanhe and Zhang, Huanling and Li, Lin and Huang, He and Guo, Hui and Zhang, Lin and Li, Chunwei and Xu, Jing-Xiao and Nie, Cai-Ping and Li, Kui and Zhang, Xiaoshi and Xia, Xiaojun and Li, Jiang
Journal: Journal for immunotherapy of cancer (2022)