α1微球蛋白(α1-MG)抗原G7023
其它名称:α1-MG抗原,α1-Microglobulin protein,human
货号:G7023
种类:抗原
应用:Standard
特异性:Human α1-Microglobulin
来源:重组蛋白
存贮:-20℃
α1微球蛋白(α1-MG)抗原G7023
产品说明
This product is for research use only. It is not intended for diagnostic or therapeutic use.
α1-MG存在于人体各种体液及淋巴细胞膜表面,血液中的α1-MG以两种形式存在,即游离的α1-MG和与IgA结合的α1-MG(α1MG-1gA)。正常情况下,α1MG-1gA约占血液中总α1-MG的40一70%,血液中免疫球蛋白水平对α1-MG及α1MG-1gA之间的比例有影响。
α1微球蛋白是一种糖蛋白,主要在肝脏及淋巴组织中合成,分布于体液及淋巴细胞膜表面。测定α1微球蛋白对诊断肾脏疾病以及评价肾功能有一定的意义。
α1微球蛋白,α1-Microglobulin protein,human
α1-Microglobulin is one of the three original members of the lipocalin superfamily. It has been found in mammals, birds, amphibians and fish and is distributed in plasma and extravascular compartments of all organs. α1-Microglobulin has a free cysteine side-chain located in a flexible loop, giving the protein reductase and dehydrogenase properties with a broad biological substrate specificity. Three lysyl residues located around the opening of the lipocalin pocket carry yellow-brown modifications originating from the binding and degradation of heme and kynurenin, the latter a tryptophan metabolite. We have suggested that α1-microglobulin is involved in defending tissues against oxidation by heme, kynurenin and reactive oxygen species.
α1微球蛋白(α1-MG)抗原G7023
注意事项:
1.本品为蛋白质制剂,未添加任何防腐剂和保护剂,在2-8℃可短期保存
2.本品作为诊断试剂原辅材料,不得直接用于诊断或治疗。