The SMM-200B Stereotaxic Micromanipulator is made for use in animal experiments with traditional methods of acute/chronic experiments or electro-physiological recording, as well as for newly developed methods of multi-photostimulations and silicon probes. It is designed without a Y-axis control knob so that two or more micromanipulators can be set close together. The upper body of SMM-200B can be tilted with dual angles: AP and ML directions simultaneously.