OnkoTec公司成立于2007年,是一家奥地利生物技术公司。基于从体液中释放出的细胞和蛋白标志物的自动分析,开发专注于癌症研究的不同疾病的快速、廉价和可靠诊断系统。OnkoTec致力于个性化的诊断应用。
产品
Onkovidon荧光染色试剂盒:
Onkovidon?green是一个长期活细胞脂质染色试剂盒
新型的近红外染料,Onkovidon?NIR-1 和 Onkovidon?NIR-2,完成口腔癌手术应用的临床前验证。
Onkovidon?plus-一个新型染色试剂盒在荧光细胞诊断学的应用目前正在临床评估中。
OnkoCell-C设备家族:
OnkoCell-C?diag是一个专门为了自动和可靠的荧光细胞诊断学研发的诊断设备。
OnkoCell-C?res是一个用于基础科学中的研究工具。
Onkovidon green产品介绍
货号:F0001
Onkovidon green活细胞膜染色试剂盒里有四瓶冻干荧光膜染料,每瓶里的荧光复合物足够制备30ml 30nM染色溶液,4度避光保存,如果保存妥当可达6个月。
Onkovidon?green是一种细胞渗透性脂质染料,在400-490nm范围之间可散发出绿色荧光,最佳的激发光谱在460nm,比如可用氩离子激光器在488nm峰值处激发。在水溶液中Onkovidon? green的最亮的荧光峰值在510nm。染料结合脂质细胞结构,比如膜,溶酶体,线粒体或脂肪体。
用Onkovidon?green染色在脂质结构与环境之间形成强烈反差和高空间分辨率。染料配方能用于几乎所有的活细胞或固定的细胞和组织的脂质结构。
Onkovidon?green也可以结合其他的染料使用,例如Hoechst 33342 (Invitrogen), LysoTracker? Red DND-99 (Invitrogen), MitoTracker? Orange CMTMRos (Invitrogen), BODIPY? 558/568 C12 (Invitrogen).
参考文献:
Onkovidon?green is patent granted for in vitro purpose only (Patent number 508680, Internationale patent for USA and EU)
Edetsberger,M. Knapp, M. Gaubitzer, G. Miksch, C. Gvichiya, K. and K?hler, G. 2011. Effective staining of tumor cells by coumarin-6 depends on the stoichiometry of cyclodextrin complex formation. Journal of Inclusion Phenomena and Macrocyclic Chemistry, 70 (3-4), pp. 327-331.
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OnkoTec
The Company: OnkoTec, founded 2007, is an Austrian biotech company.
Mission: OnkoTec develops systems for fast, inexpensive and reliable diagnosis of different diseases focusing on cancer, based on automatic analysis of released cells and protein biomarkers from body fluids.
Products: OnkoTec focuses on personalized diagnostic applications.
Onkovidon fluorescence staining kits:
·Onkovidon?green is a Long Term live cell lipid staining kit.
·Novel near-infrared dyes, Onkovidon?NIR-1 and Onkovidon?NIR-2, finished a preclinical proof for application in surgery of oral cancers.
·A novel staining kit, Onkovidon?plus is currently under clinically evaluation for use in fluorescence cytodiagnosis.
OnkoCell-C instrumentation family:
·OnkoCell-C?diag is a specially developed diagnostic device for use in automated and reliable fluorescence cytodiagnosis.
·OnkoCell-C?res is a research tool version for use in basic science.