抗人粒细胞集落刺激因子/CD114/G-CSFR鼠单抗

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产品简介

详细介绍

参考报价：电议产地：北京北京品牌：SinoBiological 型号：更新时间：2010/8/31

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Granulocyte Colony-Stimulating Factor Receptor Antibody

CD114 / G-CSFR抗体产品信息

免疫原 :	Human cell-derived rhG-CSFR extracellular domain ( Catalog #10218-HCCH )
克隆号 :	2D9G1E3
抗体宿主 :	Mouse IgG1
缓冲液 :	0.2 μm filtered solution in PBS with 5% trehalose
制备方法 :	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, human cell-derived, recombinant human G-CSFR extracellular domain (rhG-CSFR; Catalog #10218-HCCH; aa 1- 621; NP_000751.1). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.

CD114 / G-CSFR抗体使用指南

特异性 :	Human CD114 / G-CSFR
	No cross-reactivity with Human cell lysate ( 293 cell line ) in ELISA and WB.
ELISA :	This antibody can be used at 0.5/mL with the appropriate secondary reagents to detect G-CSFR. The detection limit for G-CSFR is approximately 2.5ng/well.
储存方法 :	This antibody can be stored at 2℃-8℃ for 1 month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

CD114 / G-CSFR抗体背景综述

The granulocyte colony-stimulating factor receptor (G-CSFR), also known as colony-stimulating factor 3 receptor (CSF3R) and CD114 (Cluster of Differentiation 114), is a type I transmembrane protein with an extracellular region comprised of an Ig-like domain, a cytokine receptor homologous domain, and 3 fibronectin type III domains. It is a cell-surface receptor for the granulocyte colony-stimulating factor (G-CSF). G-CSFR belongs to a family of cytokine receptors known as the hematopoietin receptor family. It is expressed on neutrophil precursors, mature neutrophils, myeloid leukemias, and placenta. It mediates G-CSF-induced myeloid cell differentiation. Mutations in the intracellular part of this receptor are associated with certain types of leukemia.

CD114 / G-CSFR抗体相关产品和研究主题

CD114 / G-CSFR 抗体相关研究领域:
- Cancer>>Growth Factor & Receptor>>CSF & Receptor>>G-CSFR/CD114
- Immunology>>Cytokine>>CSF & Receptor>>G-CSFR/CD114
- Immunology>>Cytokine>>Interleukin>>IL-6 Family Signaling Related Molecules>>G-CSFR/CD114
- Immunology>>Cluster of Differentiation>>Granulocyte CD Antigen>>Granulocyte Markers>>G-CSFR/CD114
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