| Synonyms |
ProBMP-2. |
| Description |
Pro Bone Morphogenetic Protein -2 Human Recombinant is the precursor of BMP-2 which has 3 intramolecular cystein bridges is a homodimer, non-glycosylated, polypeptide chain containing 377 amino acids and having a molecular mass of 85,476 Dalton.
Pro Bone Morphogenetic Protein 2 is purified by proprietary chromatographic techniques. |
| Source |
Escherichia Coli. |
| Physical Appearance |
Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation |
The Pro Bone Morphogenetic Protein -2 Human Recombinant was lyophilized in 0.1M K-HEPES pH 7.0 / Mannite. |
| Solubility |
It is recommended to reconstitute the lyophilized Pro Bone Morphogenetic Protein -2 Human Recombinant in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. |
| Stability |
Lyophilized Pro Bone Morphogenetic Protein -2 Human Recombinant although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Pro Bone Morphogenetic Protein -2 Human Recombinant should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles. |
| Purity |
Greater than 98.0% as determined by(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE. |
| Biological Activity |
The ProBMP-2 Human Recombinant administration leads to ectopic bone formation ion rats (Hillger et al., 2005). |
| Usage |
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY.They may not be used as drugs,agricultural or pesticidal products, food additives or household chemicals. |