| Catalogue Number |
PRO-837 |
| Synonyms |
COL4A3BP, FLJ20597, Collagen type IV alpha-3-binding protein, GPBP, STARD11, CERT, HCERT, CERTL, Ceramide Transfer Protein, Goodpasture antigen-binding protein, StAR-related lipid transfer protein 11, START domain-containing protein 11. |
| Introduction |
COL4A3BP is a kinase that particularly phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, recognized as the Goodpasture antigen that is the outcome of an autoimmune reaction directed at COL4A3BP. One isoform of COL4A3BP participates in ceramide intracellular transport. |
| Description |
COL4A3BP Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 290 amino acids (347-598 a.a.) and having a molecular mass of 33.1 kDa. The COL4A3BP is fused to 38 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. |
| Source |
Escherichia Coli. |
| Physical Appearance |
Sterile filtered colorless solution. |
| Formulation |
COL4A3BP Human solution containing 20mM Tris HCL pH-8, 0.1M NaCl, & 10% glycerol. |
| Stability |
COL4A3BP Human although stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles. |
| Purity |
Greater than 95.0% as determined by SDS-PAGE. |
| Amino acid sequence |
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWAGSMLH WPTSLPSGDA FSSVGTHRFV QKVEEMVQNH MTYSLQDVGG DANWQLVVEE GEMKVYRREV EENGIVLDPL KATHAVKGVT GHEVCNYFWN VDVRNDWETT IENFHVVETL ADNAIIIYQT HKRVWPASQR DVLYLSVIRK IPALTENDPE TWIVCNFSVD HDSAPLNNRC VRAKINVAMI CQTLVSPPEG NQEISRDNIL CKITYVANVN PGGWAPASVL RAVAKREYPK FLKRFTSYVQ EKTAGKPILF. |
| Usage |
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |