乐博现货供应美国ProSci凋亡…

乐博现货供应美国ProSci凋亡相关--APRIL(ED2)antibody
产品简介
详细介绍
  • 参考报价:2950 产地:北京北京 品牌:ProSci 型号:2415 更新时间:2012/7/18

北京乐博生物科技有限公司是美国ProSci授权一级代理商,供应其全线产品涵盖了细胞凋亡、信号传导、肿瘤、免疫、细胞生物、神经生物和传染病等领域。产品应用于ELISAWBIHCFACS等,为您的实验提供多样的检测手段,产品应用文献发表在PNASCell researchBlood……使用广泛。

抗体信息如下:

Primary Antibodies

APRIL Antibody

Background

Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for a proliferation-inducing ligand), TALL-2 (for TNF- and ApoL-related Leukocyte-expressed Ligand 2), and TRDL-1a (for TNF related death ligand 1a) in human and mouse (1-4). Two receptors for APRIL were recently identified and designated TACI and BCMA (5-7). APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-κB, and induces cell death (1-7). APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer (8,9).

 

Additional Names

APRIL (ED2)

APRIL Antibody

Description

Left: Western blot analysis of APRIL expression in Jurkat cells with APRIL antibody at 1 μg/ml (A), 2 μg/ml (B), and 4 μg/ml (C).

Below: Immunohistochemistry of APRIL in human prostate tissue with APRIL antibody at 10 μg/ml.
 

Other Product Images

Source

APRIL antibody was raised against a synthetic peptide corresponding to amino acids within an extracellular domain of human APRIL.

Purification

Affinity chromatography purified via peptide column

Clonality / Clone

This is a polyclonal antibody.

Host

APRIL antibody was raised in rabbit.

Please use anti-rabbit secondary antibodies.

Immunogen

Human APRIL (Extracellular Domain 2) Peptide (Cat. No. 2415P)

Application

APRIL antibody can be used for detection of APRIL by Western blot at 1 ?4 μg/ml.Jurkat cell lysate was used as a positive control and a 27 kDa band was detected. APRIL antibody is human, mouse and rat reactive.

Tested Application

E, WB, IHC

Buffer

Antibody is supplied in PBS containing 0.02% sodium azide.

Blocking Peptide

Cat. No. 2415P - APRIL (ED2) Peptide

Storage

APRIL antibody can be stored at 4?C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Positive Control

  1. Cat. No. 1205 - Jurkat Cell Lysate
  2. Cat. No. 1312 - Human Prostate Tissue Lysate

Species Reactivity

H, M

Protein GI Number

4507599

Protein Accession Number

NP_003799

Short Description

(ED2) A new member in the TNF family

This product belongs to the following categories:

  • Antibodies
  • Polyclonal Antibodies
  • Cytokine Antibodies
  • Cancer Antibodies

Related Products

  • APRIL (MAb Aprily-1) Antibody
    (Catalog No. XA-1019).
  • APRIL (MAb Aprily-8) Antibody
    (Catalog No. XA-1020).
  • APRIL (MAb Sacha-1) Antibody
    (Catalog No. XA-1014).
  • APRIL (MAb Sacha-2) Antibody
    (Catalog No. XA-1025).
  • APRIL Antibody
    (Catalog No. 45-272).
  • APRIL Antibody
    (Catalog No. XP-5103).
  • APRIL Antibody
    (Catalog No. 2223).
  • APRIL Antibody
    (Catalog No. XP-5103Bt).
  • APRIL Peptide
    (Catalog No. 2415P).
  • BAFF and Receptor Detection Set
    (Catalog No. PSI-1803).
  • BAFF Receptor Antibody
    (Catalog No. 3097).
  • Jurkat Cell Slide
    (Catalog No. 17-005).
  • Jurkat Lysate
    (Catalog No. 1205).
  • Prostate Lysate
    (Catalog No. 1312).

References

  1. Hahne M, Kataoka T, Schroter M, et al. APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth. J Exp Med. 1998;188(6):1185-90.
  2. Shu HB, Hu WH, Johnson H. TALL-1 is a novel member of the TNF family that is down-regulated by mitogens. J Leukoc Biol. 1999;65(5):680-3.
  3. Kelly K, Manos E, Jensen G, et al. APRIL/TRDL-1, a tumor necrosis factor-like ligand, stimulates cell death. Cancer Res. 2000;60(4):1021-7.
  4. Yu G, Boone T, Delaney J, et al. APRIL and TALL-I and receptors BCMA and TACI: system for regulating humoral immunity. Nat Immunol. 2000;1(3):252-6.



 

更多现货抗体欢迎咨询乐博生物:010-59564854

单位名称:北京乐博生物科技有限公司
详细地址:海淀区清河三街95号同源大厦912室
QQ:800107008
联系手机:
联系电话:
我要咨询:我要咨询
传真:010-58850899
Email:info@lab-bio.com