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比卢普斯罗森堡（Billups－rothenberg）公司位于美国加利福尼亚州圣迭戈州，是一家 以生产实验室培养箱，CO2培养箱实验生产线，实验生产线孵化器，实验室孵化器和昆西实验室孵化器的私营研究性公司。公司1971年成立，至今有四十年的历史。

专利，在已发表的论文中引用率在同类产品中是属于最高的，并逐渐被全球的实验科研人员 所使用。
世联博研北京科技有限公司授权在中国大陆地区独家经销缺氧\高氧培养小室及相关产品，并负责该区域售前咨询和售后的技术问题。

1. 使用方便，经济耐用，节省空间

2. 内置多用途托盘，方便放置培养皿、试管、组织培养瓶、微量板等

3. 所有组件都无毒，可酒精消毒。

4. 圆柱腔的几何形状提供了极好的气体分布。

5. 可靠的气密性密封，能 100%控制气体含量和交换，

6. 可以放置在二氧化碳培养箱内，与其他条件的形成严格对照

l Detailed SpecifiItem ：Hypoxia Modular Incubator Chamber
l Company ：Billups-Rothenberg Inc.
l Price I：inqure
l Catalog Number M：IC-101
l Catalog Number ：MIC - 101
l Exterior Dimensions Dia 31cm (12in); Height 11cm (4.7in)
l Interior Dimensions Diameter of Trays: 26.7 cm (10.5 in)
l Quantity ：EA
l Capacity 35 to 100 mm Dishes, 96 Well Plates, Flasks

2.Preconditioning of the tumor vasculature and tumor cells by intermittent hypoxia: implications for anticancer therapies
[HTML]from aacrjournals.orgP Martinive, F Defresne, C Bouzin, J Saliez, F Lair…- Cancerresearch, 2006 - AACR
... To reach and control hypoxia conditions, cells were placed in a modular incubator chamber(Billups Rothenberg, Inc., Del Mar, CA) and flushed for 10 minutes with a gas mixture of 5% CO

3.The pH-dependent membrane association of procathepsin L is mediated by a 9-residue sequence within the propeptide.
[PDF]from jbc.orgGF McIntyre, GD Godbold…- Journal of Biological Chemistry, 1994 -ASBMB
... inhibitor E-64, dithiothreitol, and HEPES were from Boehringer Mannheim; ECL WesternBlotting
Detection Re- agents and don key anti-rabbit serum conjugated to horseradish peroxi- dase were

4.Intersection of interferon and hypoxia signal transduction pathways in nitric oxide-induced tumor apoptosis

成立于1971年美国比卢普斯罗森堡公司(Billups－rothenberg)的缺氧、常氧、高氧模块化孵化室系统已用于世界各地四十年。

该公司生产的缺氧\高氧培养系统可自定义的混合气体和温度组织培养条件.密闭室已被证明安全、可靠，每个单元是一个自包含的孵化器，使您能够创建所需的组织培养的各种环境 (气体浓度和湿度)，已广泛应用于北美各大实验室和研究机构。

该产品获美国专利，在已发表的论文中引用率在同类产品中是属于最高的，并逐渐被全球的实验研人员所使用。

2010年起世联博研获得卢普斯－罗森堡公司授权在中国大陆地区独家经销缺氧\高氧培养小室及相关产品，并负责该区域售前咨询和售后的技术问题。 世联博研竭诚为全国 研工作者提供专业、周到的服务！

MIC-101模块化培养孵化室：

单流量计/双流量计系统：

流量计包括单流量计和双流量计2种，它能帮用户确定何时获得了100％气体交换。如果您使用的是模块化培养室(MIC-101)创建一个缺氧，高氧或常氧环境，我们建议您购买我们的流量计之一。这两种类型的流量计都可以把流量调整为3到25升/分钟(或0.1-10LPM)。单个流量计(SFM3001)被用来控制预混合气体的流量;双流量计(DFM3002)除了控制的气体流率还可以用来混合气体(双流量计被用作检测与氧气的组合).每个培养室的体积约8升。

热箱系统(Hot Box System)

热箱系统(Hot Box System)消除了***性气体对人员和设备的危害。
将之隔离标记实验中，让您重拾充分利用CO2培养箱作用。在热箱系统可更安全进行实验。
热箱系统包括：模块化培养室、流量计、静态热过滤器、排热过滤器、热烟道。

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The Hot Box System eliminates the hazard of contamination of personnel and equipment by radioactive gases. It isolates labeling experiments and allows you to regain full use of your CO2 incubator. Conduct experiments safely in the Hot Box System. With millions of contaminating counts generated during typical labeling experiments, incubators must be decontaminated after every use. You can now conduct safe [35S] labeling experiments at a fraction of present cost! The Hot Box System is compact and easy to use. Just place labeling experiment and a Static Hot Filter and flusk unit with desired gas mixture. Seal unit, remove Exhaust Hot Filter, and Flow Meter and place the Hot Box in a controlled temperature environment. To remove the labeled cells, reattach Exhaust Hot Filter and Flow Meter, and purge again. Dispose of both filters. It's that simple! Modular Incubator Chamber Used worldwide for two decades, this airtight chamber has been proven safe and reliable for in vitro fertilization, HIV isolation, hypoxia, organ culture and the culturing of a host of cell lines. Each unit is a self-contained incubator enabling you to create the desired tissue culture environment (gas concentrations and humidity). 货号 品名 价格 MIC-101 1 ea. Modular Incubator Chamber 询价 MIC-101 2 or more Modular Incubator Chambers 询价 One Modular Incubator Chamber consists of the following parts: Lid, base, 3 trays, stainless steel clamp, O-ring, 2 tubing clamps and tygon tubing. Conversion Kits For MIC-101: 货号 品名 价格 HMIC3S Conversion Kit with Single Flow Meter. 询价 Kit includes: 1 ea. Single Flow Meter, 1 ea. Hot Filters (5 exhaust and 5 static filter), 1 ea. Hot Chimney,2 ea. Air Filter, 1 ea. Static Filter Post,1 ea. O-Ring ? 货号 品名 价格 HMIC3 Conversion Kit With Dual Flow Meter 询价 Kit Includes: 1 ea. Dual Flow Meter, 1 ea. HOT FILTERS (5 exhaust and 5 static filter) , 1 ea. HOT CHIMNEY, 2 ea. Air Filter, 1 ea. Static Filter Post, 1 ea. O-Ring Flow Meters Regulation of gas flow during purging is required to allow sufficient reaction time for irreversible binding of [35S]-volatile with the specially formulated charcoal in the Exhaust Hot Filter. Use Single Flow Meter with pre-mixed gases or Dual Flow Meter for on-site mixing of gases. 货号 品名 价格 SFM3001 Single Flow Meter (for premixed gases) 询价 DFM3002 DFM3002 Dual Flow Meter (for mixing gases) 询价 Static Hot Filters Placed inside the chamber during experiments, the Static Hot Filter captures 85-90% of radioactive gases. Exhaust Hot Filters Any radioactive gases which have not had time to attach to the Static Hot Filter during the labeling experiment are trapped completely by the Exhaust Hot Filter during purging. Hot Chimney Used while thawing [35S]-Met/Cys, the Hot Chimney removes contaminating gases from manufacturer's reagent vial, reducing personnel exposure to radioactive gases during experimental set-up. It is designed with a Leur-Lock for safe attachment of syringe needle. Hot-Box-System： 货号 品名 价格 HBS2001S The Hot Box System With Single Flow Meter 询价 System includes: 1 ea. MIC-101 (Modular Incubator Chamber), 1 ea. Hot Filters (1 exhaust and 1 static filter) , 1 ea. Hot Chimney ,1 ea. Single Flow Meter ,2 ea. Air Filter ,1 ea. Static Filter Post NOTE: HOT FILTERS MUST BE USED IN CONJUNCTION WITH A FLOW METER. FAILURE TO DO SO MAY CAUSE BACK PRESSURE TO INCREASE RESULTING IN FAILURE OF SYSTEM. ? 货号 品名 价格 HBS2001D The Hot Box System With Dual Flow Meter 询价 System includes: 1 ea. MIC-101 (Modular Incubator Chamber), 1 ea. Hot Filters (1 exhaust and 1 static filter), 1 ea. Hot Chimney, 1 ea. Dual Flow Meter, 2 ea. Air Filter, 1 ea. Static Filter Post NOTE: HOT FILTERS MUST BE USED IN CONJUNCTION WITH A FLOW METER. FAILURE TO DO SO MAY CAUSE BACK PRESSURE TO INCREASE RESULTING IN FAILURE OF SYSTEM. To Reorder Filters: Part Number: Description: Unit Cost: HFS2020 1 Set of 5 exhaust and 5 static Hot Filters 询价 HCS2030 1 Set of 5 Hot Chimneys 询价 HFS2021 1 Set of 6 air filters 询价 replacement parts： 货号 品名 价格 102 Lid (polycarbonate) 询价 103 Base (polycarbonate) 询价 104 Tray (polycarbonate) 询价 105 Stainless Steel Ring Clamp 询价 106 O-Ring 询价 107 Tubing Clamp (10 clamps with tubing) 询价