| Fibroblast growth factor-basic (bFGF), also known as FGF-2, is a heparin-binding member of the FGF superfamily. It plays an important role in cell proliferation and differentiation associated with embryogenesis, tissue regeneration, wound healing, CNS development, angiogenesis, and tumor progression. bFGF is also a potent mitogenic agent in a wide variety of mesoderm-derived cells including BALB/c 3T3 fibroblasts, capillary and endocardial endothelial cells, myoblasts, vascular smooth muscle cells, mesothelial cells, glial and astroglial cells, and adrenal cortex cells.
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