cGAS-STING Pathway as the Target of Immunotherapy for Lung Cancer.
Authors: Dan, Qinfu and Yang, Yang and Ge, Hong
Journal: Current cancer drug targets (2023): 354-362
Spermidine enhances the efficacy of adjuvant in HBV vaccination in mice.
Authors: Ito, Daisuke and Ito, Hiroyasu and Ando, Tatsuya and Sakai, Yasuhiro and Ideta, Takayasu and Ishii, Ken J and Ishikawa, Tetsuya and Shimizu, Masahito
Journal: Hepatology communications (2023)
Discovery of podofilox as a potent cGAMP-STING signaling enhancer with antitumor activity.
Authors: Zhang, Conggang and Han, Jing and Hu, Shuiqing and Hu, Yawei and Xu, Yifang and Hou, Yanfei and Yang, Yinlong and Su, Huili and Zhang, Zhengyin and Liu, Peng and Sun, Xuxu
Journal: Cancer immunology research (2023)
Immunogenicity of small-cell lung cancer associates with STING pathway activation and is enhanced by ATR and TOP1 inhibition.
Authors: Li, Xuetao and Li, Yujun and Zhao, Ziwen and Miao, Nabo and Liu, Guorong and Deng, Liaoyuan and Wei, Shuquan and Hou, Jun
Journal: Cancer medicine (2023): 4864-4881
Model for predicting age-dependent safety and immunomodulatory effects of STING ligands in non-human primates.
Authors: Takahama, Shokichi and Ishige, Kazuya and Nogimori, Takuto and Yasutomi, Yasuhiro and Appay, Victor and Yamamoto, Takuya
Journal: Molecular therapy. Methods & clinical development (2023): 99-115
Primary role of type I interferons for the induction of functionally optimal antigen-specific CD8+ T cells in HIV infection.
Authors: Cabral-Piccin, Mariela P and Papagno, Laura and Lahaye, Xavier and Perdomo-Celis, Federico and Volant, Stevenn and White, Eoghann and Monceaux, Valérie and Llewellyn-Lacey, Sian and Fromentin, Rémi and Price, David A and Chomont, Nicolas and Manel, Nicolas and Saez-Cirion, Asier and Appay, Victor
Journal: EBioMedicine (2023): 104557
Increased LCN2 (lipocalin 2) in the RPE decreases autophagy and activates inflammasome-ferroptosis processes in a mouse model of dry AMD.
Authors: Gupta, Urvi and Ghosh, Sayan and Wallace, Callen T and Shang, Peng and Xin, Ying and Nair, Archana Padmanabhan and Yazdankhah, Meysam and Strizhakova, Anastasia and Ross, Mark A and Liu, Haitao and Hose, Stacey and Stepicheva, Nadezda A and Chowdhury, Olivia and Nemani, Mihir and Maddipatla, Vishnu and Grebe, Rhonda and Das, Manjula and Lathrop, Kira L and Sahel, José-Alain and Zigler, J Samuel and Qian, Jiang and Ghosh, Arkasubhra and Sergeev, Yuri and Handa, James T and St Croix, Claudette M and Sinha, Debasish
Journal: Autophagy (2023): 92-111
A G-quadruplex stabilizer, CX-5461 combined with two immune checkpoint inhibitors enhances in vivo therapeutic efficacy by increasing PD-L1 expression in colorectal cancer.
Authors: Chung, Shin-Yi and Chang, Yu-Chan and Hsu, Dennis Shin-Shian and Hung, Ya-Chi and Lu, Meng-Lun and Hung, Yi-Ping and Chiang, Nai-Jung and Yeh, Chun-Nan and Hsiao, Michael and Soong, John and Su, Yeu and Chen, Ming-Huang
Journal: Neoplasia (New York, N.Y.) (2023): 100856
Transforming Cold Tumors into Hot Ones with a Metal-Organic Framework-Based Biomimetic Nanosystem for Enhanced Immunotherapy.
Authors: Xu, Manman and Chang, Yincheng and Zhu, Guanghui and Zhu, Xiaoyu and Song, Xiaotong and Li, Jie
Journal: ACS applied materials & interfaces (2023): 17470-17484
Regulating T-cell metabolic reprogramming and blocking PD-1 co-promote personalized postoperative autologous nanovaccines.
Authors: Chang, Lili and Fu, Shunli and Gao, Tong and Sang, Xiao and Yang, Han and Liu, Xiaoqing and Yang, Huizhen and Liu, Yongjun and Zhang, Na
Journal: Biomaterials (2023): 122104