产品介绍
英文名称 Anti-TAS1R3
中文名称 G蛋白偶联受体TAS1R3抗体
G蛋白偶联受体TAS1R3抗体别 名 Sweet taste receptor T1R3; T1 R3; T1R 3; T1R3; TAS1 R3; TAS1R 3; TAS1R3; Taste receptor type 1 member 3; Taste receptor type 1 member 3 precursor; TR 3; TR3; TS1R3_HUMAN; .
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow
产品类型 一抗
研究领域 细胞生物 免疫学 神经生物学 信号转导 G蛋白偶联受体 G蛋白信号
蛋白分子量 predicted molecular weight: 92kDa
G蛋白偶联受体TAS1R3抗体性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human TAS1R3
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-100 ICC=1:20-100 IF=1:50-200
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 The TAS1R3 gene encodes the human homolog of mouse Sac, a major determinant of differences between sweet-sensitive and -insensitive mouse strains in their responsiveness to sucrose, saccharine, and other sweeteners (Max et al., 2001 [PubMed 11326277]).[supplied by OMIM, Jan 2010].
Function : Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose (By similarity). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.
Subunit : Forms homodimers or heterodimers with TAS1R1 and TAS1R2.
Subcellular Location : Cell membrane; Multi-pass membrane protein.
Tissue Specificity : Expressed in vascular endothelium.
Post-translational modifications : Phosphorylated by FER and other protein-tyrosine kinases. Phosphorylated at Ser-288 by PAK7/PAK5. Dephosphorylated by PTPRJ.
G蛋白偶联受体TAS1R3抗体Similarity : Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily.
Database links : UniProtKB/Swiss-Prot: Q7RTX0.2
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