产品介绍
化学名:23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine
CAS No:53123-88-9
分子式:C51H79NO13
分子量:914.17
纯度:> 99%
溶解度:Soluble to 20 mM in ethanol and to 50 mM in DMSO
保存: -20 oC
产品货号 | 品名 | 规格 | 价格和货期 |
abs810030a | Rapamycin | 5mg | 300元 (现货) |
abs810030b | Rapamycin | 10mg | 4500元 (现货) |
abs810030c | Rapamycin | 25mg | 700元 (现货) |
abs810030d | Rapamycin | 50mg | 1000元 (现货) |
abs810030e | Rapamycin | 100mg | 1400元 (现货) |
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产品描述:
Rapamycin is a macrocyclic triene antibiotic possessing potent immunosuppressant and anticancer activity.
It forms a complex with FKBP12 that binds to and inhibits the molecular target of rapamycin (mTOR).
mTOR is a member of the phosphoinositide kinase-related kinase (PIKK) family that enhances cellular
proliferation via the phosphoinositol 3-kinase/Akt signaling pathway. Inhibition of this pathway by rapamycin
blocks downstream elements that result in cell cycle arrest in G1. The effectors of mTOR action include
4EBP1 and S6K1..
Research Use only 仅限试验室研究用
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