货号: 26290 |
基因符号: ALK, CD246, NBLST3 |
描述: Anti-ALK(D1225N) Mouse Monoclonal Antibody |
背景介绍: Anaplastic lymphoma kinase (ALK) also known as CD246 (cluster of differentiation 246) is a tyrosine kinase receptor that plays an important role in the development of the brain and nervous systems. Deficiencies in ALK, which most commonly as a fusion with other genes, are indicated in cancers. |
免疫原: A synthetic peptide from the internal region of ALK, which includes the mutation of D1225N, human origin |
经过测试的应用: ELISA, WB |
推荐稀释比: ELISA: 1: 1000-1: 5000 WB: 1: 500-1: 2000 |
浓度: 1 mg/ml |
宿主: Mouse |
形式: Liquid |
克隆性: Monoclonal |
亚型: IgG |
纯度: Purified from ascites |
防腐剂: No |
成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
种属反应性: Recognizes D1225N mutant, but not wild-type ALK of vertebrates. |
储存条件: Store at -20°C. Avoid repeated freezing and thawing |
蛋白质印迹:  Purified His-tagged ALK(D1225N) protein (1060-1620aa, 68KD, lane 2) and corresponding wildtype protein (lane 1) were blotted with Anti-ALK(D1225N) monoclonal antibody (Cat. #26290). |