来宝网 2013/8/13点击1200次
pCRE-Luc
| 型号 | 载体名称 | 出品公司 | 载体用途 |
| VXC0428 | pCRE-Luc | Clontech | 信号通路报告载体 |
下载地址：http://www.chem17.com/st178406/Info_106443.html
The Agilent PathDetect in Vivo Signal Transduction Pathway cis-Reporting
Systems are designed for simple, rapid, and convenient assessment of the in
vivo activation of signal transduction pathways. We have created a series of
inducible reporter plasmids that contain the luciferase reporter gene driven
by a basic promoter element （TATA box） plus a defined inducible cisenhancer element （see Figure 2 in Appendix）. These plasmids are
particularly suited for the in vivo readouts of signal transduction pathways
since these enhancers are convergent points of many signal transduction
pathways. These systems are useful in studying the in vivo effects of a new
gene, growth factor, or drug candidate on the signaling pathway. Some of
the reporters may also be used for cloning novel signal transduction genes,
and may be useful for identifying drug candidates in a high-throughput
format.
