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心肌损伤时,心肌标志物如肌钙蛋白(cTn)、C-反应蛋白(CRP)、肌酸激酶(CK)、肌红蛋白(myoglobin)等会释放到血液中,对急性心肌梗塞检测有非常重要的作用。
现对CalBioreagentswww.biosun.cn/News/15201.htm生产的心肌损伤标志物及相关产品简介如下:
1. 心肌钙蛋白(cTn):是横纹肌收缩的重要调节蛋白,由三个亚基组成,即:肌钙蛋白C(Tnc)、肌钙蛋白T(TnT)、肌钙蛋白I(TnI)。当心肌细胞被破坏时,肌钙蛋白释放入血,其血循环中肌钙蛋白的浓度与心肌受损的程度呈正比。
ANALYTE PART # PRODUCT TYPE SPECIFICITY SOURCE PKG
Tropomyosin'' Dog A087 Protein Dog Tropomyosin'' Cardiac Dog 1 mg
Tropomyosin'' Rat A088 Protein Rat Tropomyosin'' Cardiac Rat 1 mg
Tropomysin'' Human A089 Protein Human Tropomysin'' Cardiac Human 1 mg
Troponin C A092 Protein Human Troponin C'' Cardiac Human 1 mg
Troponin C A093 Protein Human Troponin C'' Cardiac Recombinant 1 mg
Troponin C A138 Protein Rabbit Troponin C'' Skeletal Rabbit 1 mg
Troponin I 4C3 Monoclonal Human Troponin I Cardiac Mouse 1 mg
Troponin I 8H11 Monoclonal Human Troponin I Cardiac Mouse 1 mg
Troponin I 29H7 Monoclonal Human Troponin I Cardiac Mouse 1 mg
Troponin I M259 Monoclonal Human Troponin I'' Cardiac Mouse 1 mg
Troponin I M423 Monoclonal Human Troponin I'' Cardiac Mouse 1 mg
Troponin I M424 Monoclonal Human Troponin I'' Cardiac Mouse 1 mg
Troponin I M533 Monoclonal Human Troponin I'' Cardiac Mouse 1 mg
Troponin I P096 Polyclonal'' Aff. Pure Human Troponin I'' Cardiac Goat 1 mg
Troponin I A135 Protein Bovine TNI''Skeletal Bovine 1 mg
Troponin I A098 Protein Bovine Troponin I'' Cardiac Bovine 1 mg
Troponin I A099 Protein Dog Troponin I'' Cardiac Dog 1 mg
Troponin I A133 Protein Chicken TNI'' skeletal Chicken 1 mg
Troponin I A130 Protein Human TNI'' Skeletal Human 1 mg
Troponin I A094 Protein Human Troponin I'' Cardiac Human 1 mg
Troponin I A095 Protein Human Troponin I'' Cardiac Human 1 mg
Troponin I A096 Protein Human Troponin I'' Cardiac Recombinant 1 mg
Troponin I A134 Protein Monkey TNI'' Skeletal Monkey 1 mg
Troponin I A100 Protein Monkey Troponin I'' Cardiac Monkey 1 mg
Troponin I A137 Protein Mouse TNI'' Skeletal Mouse 1 mg
Troponin I A101 Protein Mouse Troponin I'' Cardiac Mouse 1 mg
Troponin I A132 Protein Porcine TNI'' Skeletal Porcine 1 mg
Troponin I A102 Protein Porcine Troponin I'' Cardiac Porcine 1 mg
Troponin I A103 Protein Rabbit Troponin I''Cardiac Rabbit 1 mg
Troponin I A136 Protein Rat TNI'' Skeletal Rat 1 mg
Troponin I A104 Protein Rat Troponin I'' Cardiac Rat 1 mg
Troponin I A131 Protein Sheep TNI'' Skeletal Sheep 1 mg
Troponin ITC complex A105 Protein Porcine Cardiac Troponin ITC complex Porcine 1 mg
Troponin ITC complex A106 Protein Rabbit Cardiac Troponin ITC complex Rabbit 1 mg
Troponin T A107 Protein Human Troponin T'' Cardiac Human 1 mg
2 肌酸激酶(CK)为细胞内重要的能量代谢酶,有三种同工酶CK-MM、CK-MB、CK-BB,主要存在于心肌细胞的外浆层,一直是临床诊断心肌损伤的心肌酶中最具特异性的酶。
ANALYTE PART # PRODUCT TYPE SPECIFICITY SOURCE PKG
CK-BB A182 Protein CK-BB'' Human Brain Human 1 mg
CK-MB M179 Monoclonal CK-MB'' Human Mouse 1 mg
CK-MB M180 Monoclonal CK-MB'' Human Mouse 1 mg
CK-MB M181 Monoclonal CK-MB'' Human Mouse 1 mg
CK-MB M182 Monoclonal CK-MB'' Human Mouse 1 mg
CK-MM M234 Monoclonal CK-MM'' Human Mouse 1 mg
CK-MM P145 Polyclonal'' Aff. Pure CK-MM'' Human Goat 1 mg
CK-MM P146 Polyclonal'' Aff. Pure CK-MM'' Human Goat 1 mg
CK-MM P195 Polyclonal'' Aff. Pure CK-MM'' Human Goat 1 mg
CK-MM P197 Neat Antiserum CK-MM'' Human Goat 1 ml
CK-MM A178 Protein CK-MM'' Human Muscle Human 1 mg
CK-MM A183 Protein CK-MM'' Human Heart Human 1 mg
3 肌红蛋白(MB)主要存在于横纹肌细胞中,当心肌细胞发生损伤时,MB是最早进入血液的生化标志物。
ANALYTE PART # PRODUCT TYPE SPECIFICITY SOURCE PKG
Myoglobin M235 Monoclonal Human Myoglobin Mouse 1 mg
Myoglobin M236 Monoclonal Human Myoglobin Mouse 1 mg
Myoglobin M237 Monoclonal Human Myoglobin Mouse 1 mg
Myoglobin P148 Polyclonal'' Aff. Pure Human Myoglobin'' Cardiac Goat 1 mg
Myoglobin A067 Protein Bovine Myoglobin Bovine 1 mg
Myoglobin A068 Protein Dog Myoglobin Dog 1 mg
Myoglobin A066 Protein Human Myoglobin'' Cardiac Human 1 mg
Myoglobin A139 Protein Monkey Myoglobin Monkey 1 mg
Myoglobin A069 Protein Mouse Myoglobin Mouse 1 mg
Myoglobin A070 Protein Porcine Myoglobin Porcine 1 mg
Myoglobin A071 Protein Rabbit Myoglobin Rabbit 1 mg
Myoglobin A072 Protein Rat Myoglobin Rat 1 mg
4 C-反应蛋白(CRP)是一种炎性标志物,CRP升高的病人,其心脏病发作、猝死及血管疾病的危险性增加。
ANALYTE PART # PRODUCT TYPE SPECIFICITY SOURCE PKG
CRP M353 Monoclonal CRP'' Human Mouse 1 mg
CRP M354 Monoclonal CRP'' Human Mouse 1 mg
CRP P104 Polyclonal'' Aff. Pure CRP'' Rat Rabbit 0.1-1mg
CRP P040 Polyclonal'' IgG CRP'' Human Rabbit 1 mg
CRP P075 Polyclonal'' IgG CRP'' Human Goat 1 mg
CRP P193 Polyclonal'' IgG CRP'' Human Goat 1 ml
CRP P224 Polyclonal'' Aff. Pure CRP'' Human Goat 1 mg
CRP P194 Neat Antiserum CRP'' Human Goat 1 ml
CRP A016 Protein CRP'' Dog Canine 0.1-1mg
CRP A017 Protein CRP'' Human Human 1 mg
CRP A019 Protein CRP'' Rat Rat 0.1-1mg
5 脂肪酸结合蛋白(FABP)是近年来发现的早期诊断急性心肌梗死较好的指标。
ANALYTE PART # PRODUCT TYPE SPECIFICITY SOURCE PKG
FABP A026 Protein Dog FABP'' Cardiac Dog 1 mg
FABP A032 Protein Human FABP'' Cardiac Human 1 mg
FABP A027 Protein Monkey FABP'' Cardiac Monkey 1 mg
FABP A028 Protein Mouse FABP'' Cardiac Mouse 1 mg
FABP A024 Protein Mouse FABP'' Liver Mouse 1 mg
FABP A029 Protein Porcine FABP'' Cardiac Porcine 1 mg
FABP A030 Protein Rabbit FABP'' Cardiac Rabbit 1 mg
FABP A031 Protein Rat FABP'' Cardiac Rat 1 mg
FABP A025 Protein Rat FABP'' Liver Rat 1 mg
FABP P097 Polyclonal'' Aff. Pure Human FABP'' Muscle Goat 1 mg